ation56.openssl.php
Mainly, there is extra verification done on the connection. This verification wasn't done on 5.5 so these issues were ignore... lhost" and apparently that causes PHP's new verification to fail.
The solution is to patch osTicket's ... rify_peer_name' => false));
This turns the verification off. For my setup, the mail server is on the s... de to PHP 5.5 which doesn't have this extra verification.
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